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Inhibition of Cdk5 induces cell death of tumor-initiating cells

Inhibition of Cdk5 induces cell death of tumor-initiating cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5379151

Inhibition of Cdk5 induces cell death of tumor-initiating cells

About this item

Full title

Inhibition of Cdk5 induces cell death of tumor-initiating cells

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2017-03, Vol.116 (7), p.912-922

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background:
Tumour-initiating cells (TICs) account for chemoresistance, tumour recurrence and metastasis, and therefore represent a major problem in tumour therapy. However, strategies to address TICs are limited. Recent studies indicate Cdk5 as a promising target for anti-cancer therapy and Cdk5 has recently been associated with epithelial–mese...

Alternative Titles

Full title

Inhibition of Cdk5 induces cell death of tumor-initiating cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5379151

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5379151

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/bjc.2017.39

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