Inhibition of Cdk5 induces cell death of tumor-initiating cells
Inhibition of Cdk5 induces cell death of tumor-initiating cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Background:
Tumour-initiating cells (TICs) account for chemoresistance, tumour recurrence and metastasis, and therefore represent a major problem in tumour therapy. However, strategies to address TICs are limited. Recent studies indicate Cdk5 as a promising target for anti-cancer therapy and Cdk5 has recently been associated with epithelial–mese...
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Full title
Inhibition of Cdk5 induces cell death of tumor-initiating cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5379151
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5379151
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2017.39