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Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5384034

Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

About this item

Full title

Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2017-04, Vol.24 (4), p.731-746

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

How metabolic pathways required for epidermal tissue growth and remodeling influence the ability of keratinocytes to survive stressful conditions is still largely unknown. The mechanistic target of rapamycin complex 2 (mTORC2) regulates growth and metabolism of several tissues, but its functions in epidermal cells are poorly defined. Rictor is an a...

Alternative Titles

Full title

Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5384034

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5384034

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/cdd.2017.8

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