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BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silico...

BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silico...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5386570

BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis

About this item

Full title

BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2017-03, Vol.8 (3), p.e2657-e2657

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Following inhalation into the lungs, silica particles are engulfed by alveolar macrophages, which triggers endogenous or exogenous apoptosis signaling pathways. As an inducer of apoptosis, the role of BBC3/PUMA (BCL2-binding component 3) in macrophages during silicosis remains unknown. Here, we exposed U937 cell-derived macrophages (UDMs) to SiO

Alternative Titles

Full title

BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5386570

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5386570

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/cddis.2017.78

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