Transition state mimics are valuable mechanistic probes for structural studies with the arginine met...
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Coactivator associated arginine methyltransferase 1 (CARM1) is a member of the protein arginine methyltransferase (PRMT) family and methylates a range of proteins in eukaryotic cells. Overexpression of CARM1 is implicated in a number of cancers, and it is therefore seen as a potential therapeutic target. Peptide sequences derived from the well-defi...
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Full title
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5389282
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5389282
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1618401114
