Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Al...
Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathology
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Abnormally hyperphosphorylated tau aggregated as intraneuronal neurofibrillary tangles is one of the two neuropathological hallmarks of Alzheimer’s disease (AD). The majority of AD cases are sporadic with numerous environmental, biological and genetic risks factors. Interestingly, insulin dysfunction and hyperglycaemia are both risk factors for spo...
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Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathology
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5389355
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5389355
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep46359
