Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic M...
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Familial hemiplegic migraine type 1 (FHM1) is a rare monogenic subtype of migraine with aura caused by mutations in
CACNA1A
that encodes the α
1A
subunit of voltage-gated Ca
V
2.1 calcium channels. Transgenic knock-in mice that carry the human FHM1 R192Q missense mutation (‘FHM1 R192Q mice’) exhibit an increased susceptibility to...
Alternative Titles
Full title
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5390001
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5390001
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-015-9681-5