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Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5390251

Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

About this item

Full title

Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-04, Vol.7 (1), p.46476, Article 46476

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

High dietary salt (NaCl) is a known risk factor for cardiovascular pathologies and inflammation. High plasma Na
+
concentrations (high Na
+
) have been shown to stiffen the endothelial cortex and decrease nitric oxide (NO) release, a hallmark of endothelial dysfunction. Here we report that chronic high Na
+
damages the endothelial...

Alternative Titles

Full title

Nanomechanics of the endothelial glycocalyx contribute to Na+-induced vascular inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5390251

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5390251

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep46476

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