Autocrine BDNF–TrkB signalling within a single dendritic spine
Autocrine BDNF–TrkB signalling within a single dendritic spine
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Live fluorescent imaging of murine hippocampal slices shows that NMDAR-dependent glutamate signalling leads to postsynaptic BDNF release, with associated signalling of its receptor, TrkB, on the same dendritic spine, suggesting autocrine BDNF signalling.
Mechanisms of neuronal plasticity
Secreted messenger molecules such as brain-derived neur...
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Full title
Autocrine BDNF–TrkB signalling within a single dendritic spine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5398094
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5398094
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19766
