Wwox–Brca1 interaction: role in DNA repair pathway choice
Wwox–Brca1 interaction: role in DNA repair pathway choice
About this item
Full title
Author / Creator
Schrock, M S , Batar, B , Lee, J , Druck, T , Ferguson, B , Cho, J H , Akakpo, K , Hagrass, H , Heerema, N A , Xia, F , Parvin, J D , Aldaz, C M and Huebner, K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In this study, loss of expression of the fragile site-encoded Wwox protein was found to contribute to radiation and cisplatin resistance of cells, responses that could be associated with cancer recurrence and poor outcome.
WWOX
gene deletions occur in a variety of human cancer types, and reduced Wwox protein expression can be detected early d...
Alternative Titles
Full title
Wwox–Brca1 interaction: role in DNA repair pathway choice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5398941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5398941
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/onc.2016.389
