A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases
A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases
About this item
Full title
Author / Creator
Zhao, Jian , Ma, Jianyang , Deng, Yun , Kelly, Jennifer A , Kim, Kwangwoo , Bang, So-Young , Lee, Hye-Soon , Li, Quan-Zhen , Wakeland, Edward K , Qiu, Rong , Liu, Mengru , Guo, Jianping , Li, Zhanguo , Tan, Wenfeng , Rasmussen, Astrid , Lessard, Christopher J , Sivils, Kathy L , Hahn, Bevra H , Grossman, Jennifer M , Kamen, Diane L , Gilkeson, Gary S , Bae, Sang-Cheol , Gaffney, Patrick M , Shen, Nan and Tsao, Betty P
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Betty Tsao, Jian Zhao, Nan Shen and colleagues show that a common missense variant in
NCF1
confers susceptibility to multiple autoimmune diseases. This variant, which leads to reduced production of reactive oxygen species, accounts for the strong association signal previously identified in the
GTF2IRD1
–
GTF2I
region at 7q11.23.
Alternative Titles
Full title
A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases
Authors, Artists and Contributors
Author / Creator
Ma, Jianyang
Deng, Yun
Kelly, Jennifer A
Kim, Kwangwoo
Bang, So-Young
Lee, Hye-Soon
Li, Quan-Zhen
Wakeland, Edward K
Qiu, Rong
Liu, Mengru
Guo, Jianping
Li, Zhanguo
Tan, Wenfeng
Rasmussen, Astrid
Lessard, Christopher J
Sivils, Kathy L
Hahn, Bevra H
Grossman, Jennifer M
Kamen, Diane L
Gilkeson, Gary S
Bae, Sang-Cheol
Gaffney, Patrick M
Shen, Nan
Tsao, Betty P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5400098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5400098
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3782
