A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human ce...
A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human cells
About this item
Full title
Author / Creator
Weng, Yanjie , Shi, Ying , Xia, Xi , Zhou, Wenjuan , Wang, Hongyan and Wang, Changyu
Publisher
Greece: Spandidos Publications
Journal title
Language
English
Formats
Publication information
Publisher
Greece: Spandidos Publications
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Scope and Contents
Contents
RNA interference (RNAi) is a powerful technology for suppressing gene function. In most studies, small interfering RNAs (siRNAs) consist of one short hairpin RNA (shRNA) and, therefore, are often unable to achieve loss-of-function of their target genes. In the current study, an RNAi vector containing three shRNAs under the control of three RNA poly...
Alternative Titles
Full title
A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5403481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5403481
Other Identifiers
ISSN
1792-1074
E-ISSN
1792-1082
DOI
10.3892/ol.2017.5672
