mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cel...
mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mannose-6-phosphate receptor (M6PR) that facilitates cellular uptake of M6P-bearing proteins, including serine-protease granzyme-B (Gzm-B) has an important role in T-cell activation, migration and contraction. However, molecular mechanisms controlling M6PR expression in T cells remain poorly understood. Here, we show that M6PR expression on T cells...
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mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5404257
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5404257
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ISSN
2056-5968
E-ISSN
2056-5968
DOI
10.1038/celldisc.2017.11
