Endocytic reawakening of motility in jammed epithelia
Endocytic reawakening of motility in jammed epithelia
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Author / Creator
Malinverno, Chiara , Corallino, Salvatore , Giavazzi, Fabio , Bergert, Martin , Li, Qingsen , Leoni, Marco , Disanza, Andrea , Frittoli, Emanuela , Oldani, Amanda , Martini, Emanuele , Lendenmann, Tobias , Deflorian, Gianluca , Beznoussenko, Galina V. , Poulikakos, Dimos , Ong, Kok Haur , Uroz, Marina , Trepat, Xavier , Parazzoli, Dario , Maiuri, Paolo , Yu, Weimiao , Ferrari, Aldo , Cerbino, Roberto and Scita, Giorgio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or rigidity transition. How cells control such phase transitions is, however, unknown. Here we show that RAB5A, a key endocytic protein, is sufficient to induce large-scale, coordinated motility over tens of cells, and ballistic motion in otherwise kinetically arr...
Alternative Titles
Full title
Endocytic reawakening of motility in jammed epithelia
Authors, Artists and Contributors
Author / Creator
Corallino, Salvatore
Giavazzi, Fabio
Bergert, Martin
Li, Qingsen
Leoni, Marco
Disanza, Andrea
Frittoli, Emanuela
Oldani, Amanda
Martini, Emanuele
Lendenmann, Tobias
Deflorian, Gianluca
Beznoussenko, Galina V.
Poulikakos, Dimos
Ong, Kok Haur
Uroz, Marina
Trepat, Xavier
Parazzoli, Dario
Maiuri, Paolo
Yu, Weimiao
Ferrari, Aldo
Cerbino, Roberto
Scita, Giorgio
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5407454
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5407454
Other Identifiers
ISSN
1476-1122
E-ISSN
1476-4660
DOI
10.1038/nmat4848