Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate r...
Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate receptor 1
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The vasculature of the central nervous system (CNS) forms a selective barrier termed the blood–brain barrier (BBB). Disruption of the BBB may contribute to various CNS diseases. Conversely, the intact BBB restricts efficient penetration of CNS-targeted drugs. Here, we report the BBB-regulatory role of endothelial sphingosine 1–phosphate (S1P) recep...
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Full title
Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate receptor 1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5410849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5410849
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1618659114