Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular...
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases
About this item
Full title
Author / Creator
Koelsche, Christian , Schrimpf, Daniel , Tharun, Lars , Roth, Eva , Sturm, Dominik , Jones, David T. W. , Renker, Eva-Kristin , Sill, Martin , Baude, Annika , Sahm, Felix , Capper, David , Bewerunge-Hudler, Melanie , Hartmann, Wolfgang , Kulozik, Andreas E. , Petersen, Iver , Flucke, Uta , Schreuder, Hendrik W. B. , Büttner, Reinhard , Weber, Marc-André , Schirmacher, Peter , Plass, Christoph , Pfister, Stefan M. , von Deimling, Andreas and Mechtersheimer, Gunhild
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
More information
Scope and Contents
Contents
Histone 3.3 (H3.3) hotspot mutations in bone tumors occur in the vast majority of giant cell tumors of bone (GCTBs; 96%), chondroblastomas (95%) and in a few cases of osteosarcomas. However, clinical presentation, histopathological features, and additional molecular characteristics of H3.3 mutant osteosarcomas are largely unknown.
In this multic...
Alternative Titles
Full title
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases
Authors, Artists and Contributors
Author / Creator
Schrimpf, Daniel
Tharun, Lars
Roth, Eva
Sturm, Dominik
Jones, David T. W.
Renker, Eva-Kristin
Sill, Martin
Baude, Annika
Sahm, Felix
Capper, David
Bewerunge-Hudler, Melanie
Hartmann, Wolfgang
Kulozik, Andreas E.
Petersen, Iver
Flucke, Uta
Schreuder, Hendrik W. B.
Büttner, Reinhard
Weber, Marc-André
Schirmacher, Peter
Plass, Christoph
Pfister, Stefan M.
von Deimling, Andreas
Mechtersheimer, Gunhild
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418758
Other Identifiers
ISSN
2045-3329
E-ISSN
2045-3329
DOI
10.1186/s13569-017-0075-5