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Methyl transfer by substrate signaling from a knotted protein fold

Methyl transfer by substrate signaling from a knotted protein fold

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5429141

Methyl transfer by substrate signaling from a knotted protein fold

About this item

Full title

Methyl transfer by substrate signaling from a knotted protein fold

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2016-10, Vol.23 (10), p.941-948

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The structurally constrained knotted configuration of the RNA methyltransferase TrmD captures the free energy of substrate binding to facilitate catalysis.
Proteins with knotted configurations, in comparison with unknotted proteins, are restricted in conformational space. Little is known regarding whether knotted proteins have sufficient dynamic...

Alternative Titles

Full title

Methyl transfer by substrate signaling from a knotted protein fold

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5429141

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5429141

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.3282

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