Methyl transfer by substrate signaling from a knotted protein fold
Methyl transfer by substrate signaling from a knotted protein fold
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The structurally constrained knotted configuration of the RNA methyltransferase TrmD captures the free energy of substrate binding to facilitate catalysis.
Proteins with knotted configurations, in comparison with unknotted proteins, are restricted in conformational space. Little is known regarding whether knotted proteins have sufficient dynamic...
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Methyl transfer by substrate signaling from a knotted protein fold
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5429141
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5429141
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3282