EZH2 alterations in follicular lymphoma: biological and clinical correlations
EZH2 alterations in follicular lymphoma: biological and clinical correlations
About this item
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Author / Creator
Huet, S , Xerri, L , Tesson, B , Mareschal, S , Taix, S , Mescam-Mancini, L , Sohier, E , Carrère, M , Lazarovici, J , Casasnovas, O , Tonon, L , Boyault, S , Hayette, S , Haioun, C , Fabiani, B , Viari, A , Jardin, F and Salles, G
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The histone methyltransferase EZH2 has an essential role in the development of follicular lymphoma (FL). Recurrent gain-of-function mutations in
EZH2
have been described in 25% of FL patients and induce aberrant methylation of histone H3 lysine 27 (H3K27). We evaluated the role of
EZH2
genomic gains in FL biology. Using RNA sequencing,...
Alternative Titles
Full title
EZH2 alterations in follicular lymphoma: biological and clinical correlations
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5436075
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5436075
Other Identifiers
ISSN
2044-5385
E-ISSN
2044-5385
DOI
10.1038/bcj.2017.32
