Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Keratinocytes undergo a unique type of programmed cell death known as cornification, which leads to the formation of the stratum corneum (SC), the main physical barrier of the epidermis. A defective epidermal barrier is a hallmark of the two most common inflammatory skin disorders, psoriasis, and atopic dermatitis. However, the detailed molecular m...
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Full title
Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5442475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5442475
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2017.56