The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines...
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
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Publisher
England: Elsevier Limited
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Language
English
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Publisher
England: Elsevier Limited
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Contents
ObjectivesThe circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms. However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their dysregulation is implicated in IVD dege...
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Full title
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5446006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5446006
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2016-209428
