Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
About this item
Full title
Author / Creator
Sangodkar, Jaya , Perl, Abbey , Tohme, Rita , Kiselar, Janna , Kastrinsky, David B. , Zaware, Nilesh , Izadmehr, Sudeh , Mazhar, Sahar , Wiredja, Danica D. , O’Connor, Caitlin M. , Hoon, Divya , Dhawan, Neil S. , Schlatzer, Daniela , Yao, Shen , Leonard, Daniel , Borczuk, Alain C. , Gokulrangan, Giridharan , Wang, Lifu , Svenson, Elena , Farrington, Caroline C. , Yuan, Eric , Avelar, Rita A. , Stachnik, Agnes , Smith, Blake , Gidwani, Vickram , Giannini, Heather M. , McQuaid, Daniel , McClinch, Kimberly , Wang, Zhizhi , Levine, Alice C. , Sears, Rosalie C. , Chen, Edward Y. , Duan, Qiaonan , Datt, Manish , Haider, Shozeb , Ma’ayan, Avi , DiFeo, Analisa , Sharma, Neelesh , Galsky, Matthew D. , Brautigan, David L. , Ioannou, Yiannis A. , Xu, Wenqing , Chance, Mark R. , Ohlmeyer, Michael , Narla, Goutham and Brookhaven National Laboratory (BNL), Upton, NY (United States)
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Targeted cancer therapies, which act on specific cancer-associated molecular targets, are predominantly inhibitors of oncogenic kinases. While these drugs have achieved some clinical success, the inactivation of kinase signaling via stimulation of endogenous phosphatases has received minimal attention as an alternative targeted approach. Here, we h...
Alternative Titles
Full title
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
Authors, Artists and Contributors
Author / Creator
Perl, Abbey
Tohme, Rita
Kiselar, Janna
Kastrinsky, David B.
Zaware, Nilesh
Izadmehr, Sudeh
Mazhar, Sahar
Wiredja, Danica D.
O’Connor, Caitlin M.
Hoon, Divya
Dhawan, Neil S.
Schlatzer, Daniela
Yao, Shen
Leonard, Daniel
Borczuk, Alain C.
Gokulrangan, Giridharan
Wang, Lifu
Svenson, Elena
Farrington, Caroline C.
Yuan, Eric
Avelar, Rita A.
Stachnik, Agnes
Smith, Blake
Gidwani, Vickram
Giannini, Heather M.
McQuaid, Daniel
McClinch, Kimberly
Wang, Zhizhi
Levine, Alice C.
Sears, Rosalie C.
Chen, Edward Y.
Duan, Qiaonan
Datt, Manish
Haider, Shozeb
Ma’ayan, Avi
DiFeo, Analisa
Sharma, Neelesh
Galsky, Matthew D.
Brautigan, David L.
Ioannou, Yiannis A.
Xu, Wenqing
Chance, Mark R.
Ohlmeyer, Michael
Narla, Goutham
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5451217
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5451217
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI89548
