The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
About this item
Full title
Author / Creator
Yip, Bon Ham , Steeples, Violetta , Repapi, Emmanouela , Armstrong, Richard N , Llorian, Miriam , Roy, Swagata , Shaw, Jacqueline , Dolatshad, Hamid , Taylor, Stephen , Verma, Amit , Bartenstein, Matthias , Vyas, Paresh , Cross, Nicholas Cp , Malcovati, Luca , Cazzola, Mario , Hellström-Lindberg, Eva , Ogawa, Seishi , Smith, Christopher Wj , Pellagatti, Andrea and Boultwood, Jacqueline
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Mutations of the splicing factor-encoding gene U2AF1 are frequent in the myelodysplastic syndromes (MDS), a myeloid malignancy, and other cancers. Patients with MDS suffer from peripheral blood cytopenias, including anemia, and an increasing percentage of bone marrow myeloblasts. We studied the impact of the common U2AF1S34F mutation on cellular fu...
Alternative Titles
Full title
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
Authors, Artists and Contributors
Author / Creator
Steeples, Violetta
Repapi, Emmanouela
Armstrong, Richard N
Llorian, Miriam
Roy, Swagata
Shaw, Jacqueline
Dolatshad, Hamid
Taylor, Stephen
Verma, Amit
Bartenstein, Matthias
Vyas, Paresh
Cross, Nicholas Cp
Malcovati, Luca
Cazzola, Mario
Hellström-Lindberg, Eva
Ogawa, Seishi
Smith, Christopher Wj
Pellagatti, Andrea
Boultwood, Jacqueline
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5451246
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5451246
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI91363
