DNA Damage-Induced Mitotic Catastrophe Is Mediated by the Chk1-Dependent Mitotic Exit DNA Damage Che...
DNA Damage-Induced Mitotic Catastrophe Is Mediated by the Chk1-Dependent Mitotic Exit DNA Damage Checkpoint
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Mitotic catastrophe is the response of mammalian cells to mitotic DNA damage. It produces tetraploid cells with a range of different nuclear morphologies from binucleated to multimicronucleated. In response to DNA damage, checkpoints are activated to delay cell cycle progression and to coordinate repair. Cells in different cell cycle phases use dif...
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Full title
DNA Damage-Induced Mitotic Catastrophe Is Mediated by the Chk1-Dependent Mitotic Exit DNA Damage Checkpoint
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_545827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_545827
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0409130102
