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Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5459528

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization

About this item

Full title

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2012-11, Vol.47 (5), p.679-687

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

The combination of chronic hypoxia and treatment of rats with the vascular endothelial growth factor (VEGF) receptor blocker, SU5416, induces pulmonary angio-obliteration, resulting in severe pulmonary arterial hypertension (PAH). Inflammation is thought to contribute to the pathology of PAH. Allergic inflammation caused by ovalbumin (OVA) immuniza...

Alternative Titles

Full title

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5459528

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5459528

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2012-0077OC

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