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The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytom...

The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5468625

The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytomegalovirus

About this item

Full title

The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytomegalovirus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (23), p.6104-6109

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Human cytomegalovirus (HCMV) strains that have been passaged in vitro rapidly acquire mutations that impact viral growth. These laboratory-adapted strains of HCMV generally exhibit restricted tropism, produce high levels of cell-free virus, and develop susceptibility to natural killer cells. To permit experimentation with a virus that retained a cl...

Alternative Titles

Full title

The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytomegalovirus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5468625

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5468625

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1704809114

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