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NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo ex...

NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5477646

NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion

About this item

Full title

NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion

Journal title

Cancer immunology, immunotherapy : CII, 2016-07, Vol.65 (9), p.1047-1059

Language

English

Formats

More information

Scope and Contents

Contents

Infusion of allogeneic NK cells is a potential immunotherapy for both hematopoietic malignancies and solid tumors. Interactions between killer immunoglobulin-like receptors (KIR) on human NK cells and KIR-ligands on tumor cells influence the magnitude of NK function. To obtain sufficient numbers of NK cells for infusion, several approaches have bee...

Alternative Titles

Full title

NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5477646

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5477646

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-016-1864-z

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