NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo ex...
NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion
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Language
English
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Contents
Infusion of allogeneic NK cells is a potential immunotherapy for both hematopoietic malignancies and solid tumors. Interactions between killer immunoglobulin-like receptors (KIR) on human NK cells and KIR-ligands on tumor cells influence the magnitude of NK function. To obtain sufficient numbers of NK cells for infusion, several approaches have bee...
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NK cells maintain licensing status and are subject to KIR/KIR-ligand inhibition following ex vivo expansion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5477646
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5477646
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ISSN
0340-7004
E-ISSN
1432-0851
DOI
10.1007/s00262-016-1864-z