Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis
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Author / Creator
Duchene, Johan , Novitzky-Basso, Igor , Thiriot, Aude , Casanova-Acebes, Maria , Bianchini, Mariaelvy , Etheridge, S Leah , Hub, Elin , Nitz, Katrin , Artinger, Katharina , Eller, Kathrin , Caamaño, Jorge , Rülicke, Thomas , Moss, Paul , Megens, Remco T A , von Andrian, Ulrich H , Hidalgo, Andres , Weber, Christian and Rot, Antal
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Genetic polymorphisms affect expression of the atypical chemokine receptor ACKR1 (Duffy) on nucleated erythrocyte precursors. Rot and colleagues show that loss of its expression alters hematopoiesis, yielding a distinct neutrophil population that rapidly exits the bloodstream to give an apparent ‘neutropenia’ phenotype.
Healthy individuals of Af...
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Full title
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480598
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3763
