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Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480598

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis

About this item

Full title

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2017-07, Vol.18 (7), p.753-761

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Genetic polymorphisms affect expression of the atypical chemokine receptor ACKR1 (Duffy) on nucleated erythrocyte precursors. Rot and colleagues show that loss of its expression alters hematopoiesis, yielding a distinct neutrophil population that rapidly exits the bloodstream to give an apparent ‘neutropenia’ phenotype.
Healthy individuals of Af...

Alternative Titles

Full title

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480598

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5480598

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3763

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