Essential role of RSK2 in c-Fos-dependent osteosarcoma development
Essential role of RSK2 in c-Fos-dependent osteosarcoma development
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Inactivation of the growth factor-regulated S6 kinase RSK2 causes Coffin-Lowry syndrome in humans, an X-linked mental retardation condition associated with progressive skeletal abnormalities. Here we show that mice lacking RSK2 develop a progressive skeletal disease, osteopenia due to impaired osteoblast function and normal osteoclast differentiati...
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Full title
Essential role of RSK2 in c-Fos-dependent osteosarcoma development
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_548699
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_548699
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/jci200522877
