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Novel molecular subgroups for clinical classification and outcome prediction in childhood medullobla...

Novel molecular subgroups for clinical classification and outcome prediction in childhood medullobla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5489698

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

About this item

Full title

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2017-07, Vol.18 (7), p.958-971

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Background International consensus recognises four medulloblastoma molecular subgroups: WNT (MBWNT ), SHH (MBSHH ), group 3 (MBGrp3 ), and group 4 (MBGrp4 ), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopathological and molecular features, and underpin curr...

Alternative Titles

Full title

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5489698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5489698

Other Identifiers

ISSN

1470-2045,1474-5488

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(17)30243-7

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