Novel molecular subgroups for clinical classification and outcome prediction in childhood medullobla...
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study
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Author / Creator
Schwalbe, Edward C, PhD , Lindsey, Janet C, PhD , Nakjang, Sirintra, PhD , Crosier, Stephen, PhD , Smith, Amanda J, MSc , Hicks, Debbie, PhD , Rafiee, Gholamreza, PhD , Hill, Rebecca M, PhD , Iliasova, Alice, MSc , Stone, Thomas, MRes , Pizer, Barry, Prof , Michalski, Antony, PhD , Joshi, Abhijit, MBBS , Wharton, Stephen B, Prof , Jacques, Thomas S, PhD , Bailey, Simon, Prof , Williamson, Daniel, PhD and Clifford, Steven C, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background International consensus recognises four medulloblastoma molecular subgroups: WNT (MBWNT ), SHH (MBSHH ), group 3 (MBGrp3 ), and group 4 (MBGrp4 ), each defined by their characteristic genome-wide transcriptomic and DNA methylomic profiles. These subgroups have distinct clinicopathological and molecular features, and underpin curr...
Alternative Titles
Full title
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study
Authors, Artists and Contributors
Author / Creator
Lindsey, Janet C, PhD
Nakjang, Sirintra, PhD
Crosier, Stephen, PhD
Smith, Amanda J, MSc
Hicks, Debbie, PhD
Rafiee, Gholamreza, PhD
Hill, Rebecca M, PhD
Iliasova, Alice, MSc
Stone, Thomas, MRes
Pizer, Barry, Prof
Michalski, Antony, PhD
Joshi, Abhijit, MBBS
Wharton, Stephen B, Prof
Jacques, Thomas S, PhD
Bailey, Simon, Prof
Williamson, Daniel, PhD
Clifford, Steven C, Prof
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5489698
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5489698
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ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(17)30243-7