Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
About this item
Full title
Author / Creator
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A 19-year-old man with leukocyte adhesion deficiency type 1 had severe periodontitis and a chronic open sacral wound that were corrected by periodic administration of ustekinumab, an antibody to interleukin-12 and interleukin-23 signaling.
LAD1 is a primary immunodeficiency resulting from mutations in
ITGB2,
which encodes the common CD18 s...
Alternative Titles
Full title
Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5494261
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5494261
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1612197
