High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded t...
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
About this item
Full title
Author / Creator
Yu, Channing , Mannan, Aristotle M , Yvone, Griselda Metta , Ross, Kenneth N , Zhang, Yan-Ling , Marton, Melissa A , Taylor, Bradley R , Crenshaw, Andrew , Gould, Joshua Z , Tamayo, Pablo , Weir, Barbara A , Tsherniak, Aviad , Wong, Bang , Garraway, Levi A , Shamji, Alykhan F , Palmer, Michelle A , Foley, Michael A , Winckler, Wendy , Schreiber, Stuart L , Kung, Andrew L and Golub, Todd R
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
A method called PRISM rapidly identifies drug candidates that are effective against specific cancer cell lines.
Hundreds of genetically characterized cell lines are available for the discovery of genotype-specific cancer vulnerabilities. However, screening large numbers of compounds against large numbers of cell lines is currently impractical, a...
Alternative Titles
Full title
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
Authors, Artists and Contributors
Author / Creator
Mannan, Aristotle M
Yvone, Griselda Metta
Ross, Kenneth N
Zhang, Yan-Ling
Marton, Melissa A
Taylor, Bradley R
Crenshaw, Andrew
Gould, Joshua Z
Tamayo, Pablo
Weir, Barbara A
Tsherniak, Aviad
Wong, Bang
Garraway, Levi A
Shamji, Alykhan F
Palmer, Michelle A
Foley, Michael A
Winckler, Wendy
Schreiber, Stuart L
Kung, Andrew L
Golub, Todd R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5508574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5508574
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3460
