Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction
Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Patients with sickle cell disease or β-thalassemia are treated with drugs that aim to reactivate production of fetal hemoglobin, but these drugs are not effective in all patients and have side effects. Lihong Shi
et al
. identify a new therapeutic strategy for these anemias, showing that a drug used to treat depression, tranylcypromine, can r...
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Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5512162
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5512162
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3101