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Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5512162

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

About this item

Full title

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2013-03, Vol.19 (3), p.291-294

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Patients with sickle cell disease or β-thalassemia are treated with drugs that aim to reactivate production of fetal hemoglobin, but these drugs are not effective in all patients and have side effects. Lihong Shi
et al
. identify a new therapeutic strategy for these anemias, showing that a drug used to treat depression, tranylcypromine, can r...

Alternative Titles

Full title

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5512162

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5512162

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3101

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