Characterization of prion-like conformational changes of the neuronal isoform of Aplysia CPEB
Characterization of prion-like conformational changes of the neuronal isoform of Aplysia CPEB
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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The protein CPEB, required for learning-related synaptic plasticity in the snail
Aplysia
, has been suggested to convert from a soluble to a prion-like state. Now these conformational forms of
Aplysia
CPEB are directly observed, with the prion form showing enhanced binding to target mRNAs.
The neuronal isoform of cytoplasmic polyaden...
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Full title
Characterization of prion-like conformational changes of the neuronal isoform of Aplysia CPEB
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5518672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5518672
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2503
