Mitochondrial replacement by pre-pronuclear transfer in human embryos
Mitochondrial replacement by pre-pronuclear transfer in human embryos
About this item
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Author / Creator
Wu, Keliang , Chen, Tailai , Huang, Sexin , Zhong, Cuiqing , Yan, Junhao , Zhang, Xiaoyu , Li, Jinsong , Gao, Yuan , Zhao, Han and Chen, Zi-Jiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
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Contents
Dear Editor, Mitochondrial DNA （mtDNA） diseases are maternally transmitted to offspring [1]. It has been proposed to pre- vent mtDNA disease inheritance through mitochondrial replacement therapy （MRT）, using nonpathogenic mito- chondria from donor oocytes to replace defective mater- nal mitochondria. Three strategies, including maternal spindle tra...
Alternative Titles
Full title
Mitochondrial replacement by pre-pronuclear transfer in human embryos
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5518873
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5518873
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2017.48
