Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associat...
Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Background:
We investigated the predictive value of dihydropyrimidine dehydrogenase (DPD) phenotype, measured as pretreatment serum uracil and dihydrouracil concentrations, for severe as well as fatal fluoropyrimidine-associated toxicity in 550 patients treated previously with fluoropyrimidines during a prospective multicenter study.
Methods:...
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Full title
Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520099
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2017.94
