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miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520159

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

About this item

Full title

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2017-07, Vol.24 (7), p.1205-1213

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis. Dysregulation of cardiac autophagy is associated with heart diseases, including cardiac hypertrophy, but the mechanism governing cardiac autophagy is rarely identified. To analyze the
in vivo
function of miR-199a in cardiac autopha...

Alternative Titles

Full title

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520159

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520159

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/cdd.2015.95

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