Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Interferon gamma (IFN
γ
) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it may enhance anti-tumor and antiviral effects of CD8 T cells. Here we investigate the mechanisms by which IFN
γ
mediates CD8 T-cell cytotoxic function. We show...
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Full title
Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5520949
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2017.67
