Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
Epigenetic heterogeneity within a tumour can play an important role in tumour evolution and the emergence of resistance to treatment. It is increasingly recognised that the study of DNA methylation (DNAm) patterns along the genome - so-called 'epialleles' - offers greater insight into epigenetic dynamics than conventional analyses which examine DNA...
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Full title
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5526259
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5526259
Other Identifiers
ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/s12859-017-1753-2
