Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeu...
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells
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Publisher
United States: Elsevier B.V
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Language
English
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Publisher
United States: Elsevier B.V
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Scope and Contents
Contents
Sphingosine 1-phosphate (S1P) plays important roles in cell proliferation, differentiation or survival mainly through its surface G-protein-coupled receptors S1P1−5. Bone represents the major site of metastasis for prostate cancer (CaP) cells, which rely on bone-derived factors to support their proliferation and resistance to therapeutics.
In th...
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Full title
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528572
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1016/j.molonc.2014.04.001