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Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeu...

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528572

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

About this item

Full title

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

Publisher

United States: Elsevier B.V

Journal title

Molecular oncology, 2014-10, Vol.8 (7), p.1181-1195

Language

English

Formats

Publication information

Publisher

United States: Elsevier B.V

More information

Scope and Contents

Contents

Sphingosine 1-phosphate (S1P) plays important roles in cell proliferation, differentiation or survival mainly through its surface G-protein-coupled receptors S1P1−5. Bone represents the major site of metastasis for prostate cancer (CaP) cells, which rely on bone-derived factors to support their proliferation and resistance to therapeutics.
In th...

Alternative Titles

Full title

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528572

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528572

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1016/j.molonc.2014.04.001

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