Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signa...
Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling
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Publisher
United States: Elsevier B.V
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Language
English
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Publisher
United States: Elsevier B.V
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Scope and Contents
Contents
Aldehyde dehydrogenase (ALDH) 1A enzymes produce retinoic acid (RA), a transcription induction molecule. To investigate if ALDH1A1 or ALDH1A3-mediated RA signaling has an active role in breast cancer tumorigenesis, we performed gene expression and tumor xenograft studies. Analysis of breast patient tumors revealed that high levels of ALDH1A3 correl...
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Full title
Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528683
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1016/j.molonc.2014.07.010