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Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signa...

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528683

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

About this item

Full title

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

Publisher

United States: Elsevier B.V

Journal title

Molecular oncology, 2015-01, Vol.9 (1), p.17-31

Language

English

Formats

Publication information

Publisher

United States: Elsevier B.V

More information

Scope and Contents

Contents

Aldehyde dehydrogenase (ALDH) 1A enzymes produce retinoic acid (RA), a transcription induction molecule. To investigate if ALDH1A1 or ALDH1A3-mediated RA signaling has an active role in breast cancer tumorigenesis, we performed gene expression and tumor xenograft studies. Analysis of breast patient tumors revealed that high levels of ALDH1A3 correl...

Alternative Titles

Full title

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528683

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5528683

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1016/j.molonc.2014.07.010

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