Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytos...
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Although antigen cross-presentation in dendritic cells (DCs) is critical to the initiation of most cytotoxic immune responses, the intracellular mechanisms and traffic pathways involved are still unclear. One of the most critical steps in this process, the export of internalized antigen to the cytosol, has been suggested to be mediated by Sec61. Se...
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Full title
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1705242114