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Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytos...

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytos...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

About this item

Full title

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (29), p.E5910-E5919

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Although antigen cross-presentation in dendritic cells (DCs) is critical to the initiation of most cytotoxic immune responses, the intracellular mechanisms and traffic pathways involved are still unclear. One of the most critical steps in this process, the export of internalized antigen to the cytosol, has been suggested to be mediated by Sec61. Se...

Alternative Titles

Full title

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1705242114

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