Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytos...
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Aside from its undisputed role in the import of newly synthesized proteins into the endoplasmic reticulum (ER), the Sec61 translocon was proposed to ensure the reverse transport of misfolded proteins to the cytosol. Based on this model, Sec61 was also proposed to be the channel exporting internalized antigens from endosomes to the cytosol, for degr...
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Full title
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5530691
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1705242114
