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Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvi...

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531412

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

About this item

Full title

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2017-08, Vol.127 (8), p.2982-2997

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The tumor microenvironment plays an important role in tumor growth and metastasis. However, the mechanism by which tumor cells regulate the cell and non-cell constituents of surrounding stroma remains incompletely understood. Promyelocytic leukemia (PML) is a pleiotropic tumor suppressor, but its role in tumor microenvironment regulation is poorly...

Alternative Titles

Full title

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531412

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI89957

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