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Histone Deacetylase Inhibitors as Anticancer Drugs

Histone Deacetylase Inhibitors as Anticancer Drugs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5535906

Histone Deacetylase Inhibitors as Anticancer Drugs

About this item

Full title

Histone Deacetylase Inhibitors as Anticancer Drugs

Publisher

Switzerland: MDPI

Journal title

International journal of molecular sciences, 2017-07, Vol.18 (7), p.1414

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Carcinogenesis cannot be explained only by genetic alterations, but also involves epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic regulation of gene expression and is controlled by the balance between histone deacetylases (HDAC) and histone acetyltransferases (HAT). HDAC inhibitors induce cancer cell cyc...

Alternative Titles

Full title

Histone Deacetylase Inhibitors as Anticancer Drugs

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5535906

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5535906

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms18071414

How to access this item