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Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5538131

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

About this item

Full title

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-04, Vol.356 (6334), p.189-194

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Single-cell genomics is important for biology and medicine. However, current whole-genome amplification (WGA) methods are limited by low accuracy of copy-number variation (CNV) detection and low amplification fidelity. Here we report an improved single-cell WGA method, Linear Amplification via Transposon Insertion (LIANTI), which outperforms existi...

Alternative Titles

Full title

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5538131

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5538131

Other Identifiers

ISSN

0036-8075,1095-9203

E-ISSN

1095-9203

DOI

10.1126/science.aak9787

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