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Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5544942

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

About this item

Full title

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-08, Vol.548 (7665), p.112-116

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glucose starvation activates AMPK via an AMP/ADP-independent mechanism that involves fructose-1,6-bisphosphate and aldolase.
New insights into AMPK activation
AMPK is a central regulator of metabolic homeostasis, and its dysfunction may result in various diseases including diabetes, obesity, and cancer. AMPK is known to be activated under str...

Alternative Titles

Full title

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5544942

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5544942

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature23275

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