Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Glucose starvation activates AMPK via an AMP/ADP-independent mechanism that involves fructose-1,6-bisphosphate and aldolase.
New insights into AMPK activation
AMPK is a central regulator of metabolic homeostasis, and its dysfunction may result in various diseases including diabetes, obesity, and cancer. AMPK is known to be activated under str...
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Full title
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5544942
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5544942
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature23275
