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A distinct subpopulation of CD25⁻ T-follicular regulatory cells localizes in the germinal centers

A distinct subpopulation of CD25⁻ T-follicular regulatory cells localizes in the germinal centers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5547636

A distinct subpopulation of CD25⁻ T-follicular regulatory cells localizes in the germinal centers

About this item

Full title

A distinct subpopulation of CD25⁻ T-follicular regulatory cells localizes in the germinal centers

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (31), p.E6400-E6409

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

T-follicular helper (Tfh) cells differentiate through a multistep process, culminating in germinal center (GC) localized GC-Tfh cells that provide support to GC-B cells. T-follicular regulatory (Tfr) cells have critical roles in the control of Tfh cells and GC formation. Although Tfh-cell differentiation is inhibited by IL-2, regulatory T (Treg) ce...

Alternative Titles

Full title

A distinct subpopulation of CD25⁻ T-follicular regulatory cells localizes in the germinal centers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5547636

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5547636

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1705551114

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