Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-posi...
Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial
About this item
Full title
Author / Creator
Baselga, José, Prof , Im, Seock-Ah, Prof , Iwata, Hiroji, MD , Cortés, Javier, MD , De Laurentiis, Michele, MD , Jiang, Zefei, Prof , Arteaga, Carlos L, Prof , Jonat, Walter, Prof , Clemons, Mark, Prof , Ito, Yoshinori, MD , Awada, Ahmad, Prof , Chia, Stephen, MD , Jagiełło-Gruszfeld, Agnieszka, MD , Pistilli, Barbara, MD , Tseng, Ling-Ming, MD , Hurvitz, Sara, MD , Masuda, Norikazu, MD , Takahashi, Masato, MD , Vuylsteke, Peter, MD , Hachemi, Soulef, PhD , Dharan, Bharani, MS , Di Tomaso, Emmanuelle, PhD , Urban, Patrick, MD , Massacesi, Cristian, MD and Campone, Mario, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Phosphatidylinositol 3-kinase (PI3K) pathway activation is a hallmark of endocrine therapy-resistant, hormone receptor-positive breast cancer. This phase 3 study assessed the efficacy of the pan-PI3K inhibitor buparlisib plus fulvestrant in patients with advanced breast cancer, including an evaluation of the PI3K pathway activati...
Alternative Titles
Full title
Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Im, Seock-Ah, Prof
Iwata, Hiroji, MD
Cortés, Javier, MD
De Laurentiis, Michele, MD
Jiang, Zefei, Prof
Arteaga, Carlos L, Prof
Jonat, Walter, Prof
Clemons, Mark, Prof
Ito, Yoshinori, MD
Awada, Ahmad, Prof
Chia, Stephen, MD
Jagiełło-Gruszfeld, Agnieszka, MD
Pistilli, Barbara, MD
Tseng, Ling-Ming, MD
Hurvitz, Sara, MD
Masuda, Norikazu, MD
Takahashi, Masato, MD
Vuylsteke, Peter, MD
Hachemi, Soulef, PhD
Dharan, Bharani, MS
Di Tomaso, Emmanuelle, PhD
Urban, Patrick, MD
Massacesi, Cristian, MD
Campone, Mario, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5549667
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5549667
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(17)30376-5
