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Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of...

Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5561929

Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1

About this item

Full title

Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1

Publisher

Greece: D.A. Spandidos

Journal title

Molecular medicine reports, 2017-08, Vol.16 (2), p.1785-1792

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

Homeostasis of cholesterol is regulated by absorption in the intestine and synthesis in the liver. The authors previously demonstrated that OPN (osteopontin) exhibits the ability to alter hepatic cholesterol metabolism, thus affecting cholesterol gallstone formation in mice. The present study investigated the role of OPN in cholesterol gallstone fo...

Alternative Titles

Full title

Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5561929

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5561929

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2017.6774

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