Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous...
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
About this item
Full title
Author / Creator
Workman, Michael J , Mahe, Maxime M , Trisno, Stephen , Poling, Holly M , Watson, Carey L , Sundaram, Nambirajan , Chang, Ching-Fang , Schiesser, Jacqueline , Aubert, Philippe , Stanley, Edouard G , Elefanty, Andrew G , Miyaoka, Yuichiro , Mandegar, Mohammad A , Conklin, Bruce R , Neunlist, Michel , Brugmann, Samantha A , Helmrath, Michael A and Wells, James M
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Organoids formed by combining pluripotent-stem-cell-derived human neural crest cells with pluripotent-stem-cell-derived intestinal tissue show functional interstitial cells of Cajal and undergo waves of contraction; these tissues reveal insights into the molecular defects characterizing Hirschsprung's disease.
The enteric nervous system (ENS) of...
Alternative Titles
Full title
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
Authors, Artists and Contributors
Author / Creator
Mahe, Maxime M
Trisno, Stephen
Poling, Holly M
Watson, Carey L
Sundaram, Nambirajan
Chang, Ching-Fang
Schiesser, Jacqueline
Aubert, Philippe
Stanley, Edouard G
Elefanty, Andrew G
Miyaoka, Yuichiro
Mandegar, Mohammad A
Conklin, Bruce R
Neunlist, Michel
Brugmann, Samantha A
Helmrath, Michael A
Wells, James M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5562951
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5562951
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X,1744-7933
DOI
10.1038/nm.4233
