Detecting circular RNAs: bioinformatic and experimental challenges
Detecting circular RNAs: bioinformatic and experimental challenges
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
In 2012, genome-wide statistical analysis of splicing led to the discovery of the global expression of circular RNA (circRNA) in eukaryotes and found that, in hundreds of human genes, circRNA constitutes the major isoform. circRNA expression was previously overlooked owing to a combination of biases in library preparation and heuristi...
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Full title
Detecting circular RNAs: bioinformatic and experimental challenges
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5565156
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5565156
Other Identifiers
ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/nrg.2016.114
