New insights into the imprinted MEG8-DMR in 14q32 and clinical and molecular description of novel pa...
New insights into the imprinted MEG8-DMR in 14q32 and clinical and molecular description of novel patients with Temple syndrome
About this item
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Author / Creator
Beygo, Jasmin , Küchler, Alma , Gillessen-Kaesbach, Gabriele , Albrecht, Beate , Eckle, Jonas , Eggermann, Thomas , Gellhaus, Alexandra , Kanber, Deniz , Kordaß, Ulrike , Lüdecke, Hermann-Josef , Purmann, Sabine , Rossier, Eva , van de Nes, Johannes , van der Werf, Ilse M , Wenzel, Maren , Wieczorek, Dagmar , Horsthemke, Bernhard and Buiting, Karin
Publisher
England: Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
England: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
The chromosomal region 14q32 contains several imprinted genes, which are expressed either from the paternal (DLK1 and RTL1) or the maternal (MEG3, RTL1as and MEG8) allele only. Imprinted expression of these genes is regulated by two differentially methylated regions (DMRs), the germline DLK1/MEG3 intergenic (IG)-DMR (MEG3/DLK1:IG-DMR) and the somat...
Alternative Titles
Full title
New insights into the imprinted MEG8-DMR in 14q32 and clinical and molecular description of novel patients with Temple syndrome
Authors, Artists and Contributors
Author / Creator
Küchler, Alma
Gillessen-Kaesbach, Gabriele
Albrecht, Beate
Eckle, Jonas
Eggermann, Thomas
Gellhaus, Alexandra
Kanber, Deniz
Kordaß, Ulrike
Lüdecke, Hermann-Josef
Purmann, Sabine
Rossier, Eva
van de Nes, Johannes
van der Werf, Ilse M
Wenzel, Maren
Wieczorek, Dagmar
Horsthemke, Bernhard
Buiting, Karin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5567157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5567157
Other Identifiers
ISSN
1018-4813
E-ISSN
1476-5438
DOI
10.1038/ejhg.2017.91
